The diary details Emlen's travels in rural Pennsylvania to small towns and settlements of fellow Quakers. Entries often describe tensions and interactions between white settlers and Indigenous populations. Treaties between white settlers and native groups are also discussed.

William Savery's diaries. The majority of the first volume concerns the Treaty at Canandaigua, and the remaining volumes are accounts of religious visits Savery made throughout Europe. Entries generally describe details of travel between destinations, Quaker meetings attended, Quaker families visited, and descriptions of each location's culture, food, language, style of dress, and form of local government.

Primarily the letters of the Quaker Scattergood family detailing daily life in the Philadelphia area and touching on issues of dress. There is a also a letter of Joseph Scattergood from Tunesassa, New York, telling of his work with Cornplanter's Native Americans. As well, there is a diary kept by Ann Sellers from 1853 to 1856 and a cookbook, circa 1800.

Entries describe Sharpless's travel to, and time spent in, Cornplanter's village during 1798.

Henry Simmons was a Quaker missionary to the Seneca Nation and a member Middletown Monthly Meeting. Henry Simmons's journals are related to time Simmons spent with the Oneida and Seneca nations.

Joel Swayne's diary entries describe his journey to the Seneca nation and the two years he spent there. Swayne provides detailed descriptions of Cornplanter (Gaiänt'wakê), the chief, his family, the village and villagers, cultural differences between the Quakers and the Senecas, the difficulty of the language barrier, and discussions between Quaker missionaries and Seneca members.

Thomas Wistar's journal entries largely describe his work as an Indian Commissioner, including visits to Washington D.C., the Seneca Nation, the Wichita Indian Agency, and other Native American Reservations. In addition to his work as a commissioner, entries detail social calls with family and friends, descriptions of Quaker meetings, and religious reflection and prayers.