The collectionn contains Mekeel's notes and abstracts concerning Quaker meetings in the Scipio and Farmington Quarterly Meetings of New York Yearly Meeting, particularly concerning the various nineteenth century Orthodox separations. There is also a small group of correspondence focused on Quaker meeting records.

The collection contains a small number of miscellaneous papers relating to efforts within New York Yearly Meeting to support the manumission of enslaved people, abolition, and education of formerly enslaved people, 1778-1870. Most are copies of reports presented to New York Monthly Meeting or to the Yearly Meeting, compiled as a reference file.